CURRENT POSITION 
Assistant Professor of Instrumental Pharmaceutical Analysis (tenure track), Department of Pharmacy, University of Patras.

EDUCATION / RESEARCH TRAINING
2010: Research fellow, University of Michigan, Department of Chemistry, Advanced Raman Microscopy & Chemical Imaging Lab (Prof. Michael D. Morris).
2000: Ph.D. in Chemical Engineering, University of Patras.
1994: Diploma in Chemical Engineering, University of Patras (five years curriculum).

AWARDS

• Award in Panhellenic Contest for Advanced Research and Innovation of Eurobank EFG Group and SEV (Hellenic Federation of Enterprises) «Give Greece A Chance» 2011, for the application of biomedical technologies for the quick, reliable and secure diagnosis of retrogressive (osteoarthritis) and metabolic (osteoporosis) bone disorders (Coordinator: Sofia Panteliu, Department of Mechanical Engineering and Aeronautics, Univ. Patras).
• Fellowship from the Institute Francais du Petrole, Rueil Malmaison, France, 1997.
• Scholarship from ICE/HT - FORTH, 1994-2000.
• Scholarship from ESF (European Science Foundation), 2001.

TEACHING ACTIVITIES

Undergraduate Courses

• PHA-C14-NEW «Spectroscopy» (Theory and Lab) 
• PHA-C21-NEW «Separation and Electrochemical techniques» (Theory and Lab) 
• PHA-B13-NEW «Physical Chemistry» (Theory and Lab)

Graduate Courses

 Graduate Program: Drug Discovery & Development  

• DPHA_3 «Pharmaceutical Analysis - Biospectroscopy» 
• DPHA_B03 «Applied Pharmaceutical Analysis – Characterization of Formulations» Graduate Program: Cosmetology: Synthesis & Assessment of Cosmetic Products 
• PHA-COS-23 «Methods of Instrumental Analysis of Cosmetic Products»

RESEARCH INTERESTS AND ACTIVITIES

• Development of novel methodologies based on Raman and IR spectroscopy for the detection and quantitative determination of substances in biological liquids. Substances of interest: antibodies, alcohols, pharmaceutical active substances. Biological fluids of interest: blood serum, saliva, urine, aqueous humor.  
• Characterization of polymorphic phases (generic drugs). 
• Study of bone and cartilage diseases (osteoporosis, osteoarthritis) using spectroscopic and X-ray imaging techniques. Scope: the development of a methodology for the diagnosis and monitoring of pathological situations in no or minimally invasive way.
• Study of the chemical changes induced to bones or joints of lab animals by the deficiency of genes. Use of Raman spectroscopy and micro Computed Tomography.
• Monitoring of crack healing in animal femurs.

PARTICIPATION IN RESEARCH PROGRAMS

• «K. Karatheodori» project entitled: «Development of Novel Diagnostic Method for Monitoring Bone Diseases», Contract No: C.914, Duration: 01.05.2010 to 01.05.2013, (coordinator).
• «Heracleitus II» project entitled: «Drug Release from Biodegradable Polymers» Contract No: 119, Duration: 17.02.2009 to 31.08.2013.
• «ENVIRONMENT AND CLIMATE» project entitled: «Novel Remediation Strategies for Preservation of Marble Structures Endangered from Environmental Damages» Contract No: ENV4-CT98-0704, Duration: 01.07.1998 to 31.05.2001.
• «NATO» project entitled: «Improvement of the Technological Parameters in the Electrochemical Production Mg-Nd Alloys», Contract No: SFP-971858, Duration: 01.06.2001 to 31.10.2001.
• «EPET II» project entitled: «Development of New Materials for Structural Surface Conservation of Monuments», Contract No: 365/95, Duration: 01.07.1995 to 31.12.1995.
• «JOULE» project entitled: «Control of Corrosion and Scaling in Geothermal Systems» Contract No: JOU2-CT92-0108, Duration: 01.10.1994 to 30.06.1995.
• «BRITE-EURAM» project entitled: «High Performance Coating Materials for Application in Corrosive and Abrasive Environments (HIPERMAT)», Contract No: BREU-0118-C (GDF), Duration: 01.06.1990 to 31.05.1993.

PARTICIPATION IN RESEARCH NETWORKS
Intra-University Research Network entitled: «Network for the study of retrogressive and metabolic disorders of bone and cartilage - OSTEONET».

PUBLICATIONS
Publications in Journals: 28
Participations in Conferences: 85
Citations: 400
Other Publications: 2
Chapters in Books: 2

SELECTED PUBLICATIONS

1. Eleni Kamilari, Konstantinos Farsalinos, Konstantinos Poulas, Christos G. Kontoyannis, Malvina G. Orkoula, “Detection and quantitative determination of heavy metals in electronic cigarette refill liquids using Total Reflection X-ray Fluorescence Spectrometry”, Food and Chemical Toxicology, 116, Part B, (2018) 233–237 https://doi.org/10.1016/j.fct.2018.04.035.
2. Harry Blair, Elena Kalyvioti, Nicholaos Papachristou, Irina Tourkova, Spyros Syggelos, Despina Deligianni, Malvina Orkoula, Christos Kontoyannis, Eleni Karavia, Kyriakos Kypreos, and Dionysios Papachristou «Apolipoprotein A-1 (ApoA-1) Regulates Osteoblast and Lipoblast Precursor Cells in Mice», Laboratory Investigation, 96 (2016) 763-772 doi:10.1038/labinvest.2016.51 (2016) doi:10.1038/labinvest.2016.51.
3. Malvina G. Orkoula and Christos G. Kontoyannis, «Raman Spectroscopy for the Study of Biological Organisms (Biogenic Materials and Biological Tissues): A Valuable Analytical Tool», Spectroscopy Europe, 26 (2014) 18-21. 
4. Malvina G. Orkoula, Martha Z. Vardaki and Christos G. Kontoyannis, «Study of Bone Matrix Changes Induced by Osteoporosis in Rat Tibia Using Raman Spectroscopy», Vibrational Spectroscopy 63 (2012) 404-408. 
5. Malvina Orkoula, Michael Friedman, David Kohn and Michael Morris, «Effect pf Exercise and Nutrition on Composition of Murine Tibia» Bone, 48 (2011) S179 Suppl.2.

Office Hours for Students
Wednesday 12:00-14:00
Thursday 12:00-13:00